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The DNA model shown (far right) is a space-filling, or CPK, model of the DNA double helix. Animated molecular models, such as the wire, or skeletal, type shown at the top of this article, allow one to visually explore the three-dimensional (3D) structure of DNA. Another type of DNA model is the space-filling, or CPK, model.
K80, the Kimura 1980 model, [3] often referred to as Kimura's two parameter model (or the K2P model), distinguishes between transitions (, i.e. from purine to purine, or , i.e. from pyrimidine to pyrimidine) and transversions (from purine to pyrimidine or vice versa). In Kimura's original description of the model the α and β were used to ...
Molecular models may be created for several reasons – as pedagogic tools for students or those unfamiliar with atomistic structures; as objects to generate or test theories (e.g., the structure of DNA); as analogue computers (e.g., for measuring distances and angles in flexible systems); or as aesthetically pleasing objects on the boundary of ...
Modern biology and biochemistry make intensive use of these techniques in recombinant DNA technology. Recombinant DNA is a man-made DNA sequence that has been assembled from other DNA sequences. They can be transformed into organisms in the form of plasmids or in the appropriate format, by using a viral vector. [159]
The two base-pair complementary chains of the DNA molecule allow replication of the genetic instructions. The "specific pairing" is a key feature of the Watson and Crick model of DNA, the pairing of nucleotide subunits. [5] In DNA, the amount of guanine is equal to cytosine and the amount of adenine is equal to thymine. The A:T and C:G pairs ...
The third stage includes different models of DNA and amino acid substitution. Several models of substitution exist. A few examples include Hamming distance, the Jukes and Cantor one-parameter model, and the Kimura two-parameter model (see Models of DNA evolution). The fourth stage consists of various methods of tree building, including distance ...
A geometrical model of a DNA tetrahedron described in Goodman, 2005. [10] Models of this type are useful for ensuring that tertiary structure constraints do not cause excessive strain to the molecule. Geometrical models of nucleic acids are used to predict tertiary structure. This is important because designed nucleic acid complexes usually ...
Population genetics is a subfield of genetics that deals with genetic differences within and among populations, and is a part of evolutionary biology.Studies in this branch of biology examine such phenomena as adaptation, speciation, and population structure.