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Mebendazole (MBZ), sold under the brand name Vermox among others, is a medication used to treat a number of parasitic worm infestations. [5] This includes ascariasis , pinworm infection , hookworm infections , guinea worm infections and hydatid disease , among others. [ 5 ]
From top to bottom: mebendazole (P), amlodipine (POM), diazepam (POM), paracetamol (GSL). Over-the-counter ( OTC ) drugs are medicines sold directly to a consumer without a requirement for a prescription from a healthcare professional, [ 1 ] as opposed to prescription drugs , which may be supplied only to consumers possessing a valid prescription.
It is available for human use to treat worm infections. In certain countries such as France, it is inexpensive and available OTC (without prescription) [3] under the brand name Fluvermal as an alternative to mebendazole which is not currently sold there. [4]
Albendazole is a broad-spectrum antihelmintic and antiprotozoal agent of the benzimidazole type. [3] It is used for the treatment of a variety of intestinal parasite infections, including ascariasis, pinworm infection, hookworm infection, trichuriasis, strongyloidiasis, taeniasis, clonorchiasis, opisthorchiasis, cutaneous larva migrans, giardiasis, and gnathostomiasis, among other diseases.
4‑Hydroxyacetamide (1) is alkylated with n-propyl bromide in the presence of potassium hydroxide to give the ether (2).Nitration of this product with nitric and sulfuric acids proceeds at the position ortho to the amide group (3), which is then reduced with SnCl 2 to yield the phenylenediamine derivative (4).
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