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Side effects from intra-articular administration can include joint pain, swelling, lameness, and, rarely, infection of the joint. Intramuscular injection can cause dose-dependent inflammation and bleeding, since PSGAG is an analogue of the anticoagulant heparin. [4] In dogs, this may manifest as bleeding from the nose or as bloody stools. [7]
In worst-case scenarios, pain can cause a dog to be more irritable and aggressive, like if a human had a severe headache and couldn't tolerate social interaction, Enomoto said. ... Nearly 40% of ...
A: There are many possible causes of limping in the back legs and dragging the back legs in a dog this age: Arthritis: When senior dogs develop changes in their vertebral bones, their spine can be ...
Hip dysplasia is a defect in the shape of the hip joint which can, depending on the degree of hip luxation, be quite painful to the dog as it ages. Over time it often causes arthritis in the hips. Dysplasia can also occur in the elbow joint. Luxating patellas can be a problem for smaller breeds. It can cause lameness and pain in the hind legs.
The effect of chondroitin sulfate in people with osteoarthritis is likely the result of a number of reactions including its anti-inflammatory activity, the stimulation of the synthesis of proteoglycans and hyaluronic acid, and the decrease in catabolic activity of chondrocytes, inhibiting the synthesis of proteolytic enzymes, nitric oxide, and ...
“Moreover, they can cause side effects such as diarrhea, constipation, abdominal pain and even allergic reactions in some individuals.” Related: The Best & Worst Foods for Your Joints. 2 ...