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Coronary artery disease (CAD) is the most common cause of coronary ischemia. [7] Coronary ischemia and coronary artery disease are contributors to the development of heart failure over time. [ 10 ] Diagnosis of coronary ischemia is achieved by an attaining a medical history and physical examination in addition to other tests such as ...
Coronary artery disease is the leading cause of death for both males and females and accounts for approximately 600,000 deaths in the United States every year. [139] According to present trends in the United States, half of healthy 40-year-old males will develop CAD in the future, and one in three healthy 40-year-old females. [ 140 ]
[14] [15] Coronary artery disease and stroke account for 80% of CVD deaths in males and 75% of CVD deaths in females. [3] Most cardiovascular disease affects older adults. In the United States 11% of people between 20 and 40 have CVD, while 37% between 40 and 60, 71% of people between 60 and 80, and 85% of people over 80 have CVD. [2]
Coronary artery disease is the leading cause of death in men and women. [16] This condition is the cause of one third of all deaths, which is especially worse in areas with lower socioeconomic status. [16] Mortality is nearly five times higher in men than women, but mortality difference narrows with age. [16]
Risk factors for CAD include smoking, [26] high cholesterol, obesity, and family history of CAD. Primarily, the accumulation of cholesterol in the bloodstream from high-fat diets lead to atherosclerotic occlusion and its clinical consequences. Therefore, preventative measures for CAD mainly involve diet changes.
If a patient has a strong family history of a particular disorder (or group of disorders), this will generally lead to a lower threshold for investigating symptoms or initiating treatment. This is seen particularly in cardiac disease, where strong family history is considered a significant cardiovascular risk factor.
Their results indicated that CABG is a better option for CAD patients. [17] A trial published in 2021, comparing results after one year, also concluded that CABG is a safer option than PCI. [18] A large study published in 2023 showed that PCI patients had higher mortality than CABG patients with left main coronary artery disease. [19]
The well-established indications for the use of the CAC score include stratification of global cardiovascular risk for asymptomatic patients: intermediate risk based on the Framingham risk score (class I); low risk based on a family history of early coronary artery disease (CAD) (class IIa); and low-risk patients with diabetes (class IIa).