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Guaifenesin might act as an expectorant by increasing the volume and reducing the viscosity of secretions in the trachea and bronchi via stimulation of the gastric mucosa. . This stimulation leads to an increased parasympathetic activity in the respiratory tract via the so-called gastro-pulmonary reflex, although some in vitro studies suggested that it might also act directly on the ...
The first plateau (1.5 to 2.5 mg per kg body weight) is described as having euphoria, auditory changes, mild stimulation, and change in perception of gravity. The second plateau (2.5 to 7.5 mg/kg) causes intense euphoria, vivid imagination, and closed-eye hallucinations.
EDS can affect the ability to function in family, social, occupational, or other settings. [1] [2] A proper diagnosis of the underlying cause and ultimately treatment of symptoms and/or the underlying cause can help mitigate such complications. [3] According to the National Sleep Foundation, around 20 percent of people experience EDS. [4]
Some placebo-controlled trials have found that it is ineffective against some forms of cough, including acute cough in children. [14] [15] It is thus not recommended for children. [15] [16] Additionally, there is no evidence that hydrocodone is useful in children. [17] Similarly, a 2012 Dutch guideline does not recommend its use to treat acute ...
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“It's based on a lot of speculation, and until we have really good data, I don't think that people should get overly excited about Mucinex because, you know, it's an over-the-counter medication.
Next day drowsiness is common and may increase during the initial phase of treatment as accumulation occurs until steady-state plasma levels are attained. A 2009 meta-analysis found a 44% higher rate of mild infections , such as pharyngitis or sinusitis , in people taking hypnotic drugs compared to those taking a placebo.
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