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  2. Intestinal epithelium - Wikipedia

    en.wikipedia.org/wiki/Intestinal_epithelium

    In the small intestine, M cells are associated with Peyer's patches. Cup cells are a distinct cell type that produces vimentin. [13] Tuft cells play a part in the immune response. [13] Throughout the digestive tract, the distribution of the different types of epithelial cells varies according to the function of that region. [5]

  3. Enterocyte - Wikipedia

    en.wikipedia.org/wiki/Enterocyte

    Intestinal stem cell aging has been studied in Drosophila as a model for understanding the biology of stem cell/niche aging. [4] Using knockdown mutants defective in various genes that function in the DNA damage response in enterocytes, it was shown that deficiency in the DNA damage response accelerates intestinal stem cell aging, thus ...

  4. Intestinal gland - Wikipedia

    en.wikipedia.org/wiki/Intestinal_gland

    The glands and intestinal villi are covered by epithelium, which contains multiple types of cells: enterocytes (absorbing water and electrolytes), goblet cells (secreting mucus), enteroendocrine cells (secreting hormones), cup cells, myofibroblast, tuft cells, and at the base of the gland, Paneth cells (secreting anti-microbial peptides) and ...

  5. Gastrointestinal wall - Wikipedia

    en.wikipedia.org/wiki/Gastrointestinal_wall

    Function Absorptive cell: Epithelium/intestinal glands: Digestion and absorption of nutrients in chyme Goblet cell: Epithelium/intestinal glands: Secretion of mucus Paneth cell: Intestinal glands: Secretion of the bactericidal enzyme lysozyme; phagocytosis G cells: Intestinal glands of duodenum: Secretion of the hormone intestinal gastrin: I cells

  6. Intestinal mucosal barrier - Wikipedia

    en.wikipedia.org/wiki/Intestinal_mucosal_barrier

    The central component is the intestinal epithelial layer, which provides physical separation between the lumen and the body. The secretion of various molecules into the lumen reinforces the barrier function on the extra-epithelial side, while a variety of immune cells provide additional protection below the epithelial layer. [3] [5] [6]

  7. List of intestinal epithelial differentiation genes - Wikipedia

    en.wikipedia.org/wiki/List_of_intestinal...

    Involves in epithelial cell maturation as well as goblet and Paneth cell differentiation. Required for the small intestinal identity during development. In IEC-6 cells, conditional expression induced enterocyte and goblet like cells: 21081128 [13] 19386267 [14] 8552090 [15] CTNNB1: Catenin, beta: Paneth cell differentiation. Essential for stem ...

  8. Paneth cell - Wikipedia

    en.wikipedia.org/wiki/Paneth_cell

    Like the other epithelial cell lineages in the small intestine, Paneth cells originate at the stem cell region near the bottom of the gland. [4] There are on average 5–12 Paneth cells in each small intestinal crypt. [5] Unlike the other epithelial cell types, Paneth cells migrate downward from the stem cell region and settle just adjacent to ...

  9. Brush border - Wikipedia

    en.wikipedia.org/wiki/Brush_border

    Brush border cells are found mainly in the following organs: The small intestine tract: This is where absorption takes place. [2] [3] [4] The brush borders of the intestinal lining are the site of terminal carbohydrate digestions. The microvilli that constitute the brush border have enzymes for this final part of digestion anchored into their ...