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Benign prostatic hyperplasia (BPH), also called prostate enlargement, is a noncancerous increase in size of the prostate gland. [1] Symptoms may include frequent urination , trouble starting to urinate, weak stream, inability to urinate , or loss of bladder control . [ 1 ]
It often enlarges as men age, most commonly as benign tissue growth — called benign prostatic hyperplasia, or BPH. In fact, about half of men have BPH by age 60, and over three-quarters after 70.
A number of medications can be used which need to be tailored to each person's needs and types of symptoms (according to UPOINTS, S = sexual: e.g. erectile dysfunction, ejaculatory dysfunction, postorgasmic pain). [56] Treatment with antibiotics is controversial. A review from 2019 indicated that antibiotics may reduce symptoms.
The 5α-reductase inhibitors finasteride and dutasteride are used to treat benign prostatic hyperplasia, a condition in which the prostate becomes enlarged and this results in urinary obstruction and discomfort. [37] They are effective because androgens act as growth factors in the prostate gland. [37]
Post-finasteride syndrome or PFS refers to a range of physical, and mental health symptoms associated with the use of finasteride as a treatment for hair loss and benign prostatic hyperplasia.
Urinary retention, including drug-induced cases, may be an early sign of benign prostatic hyperplasia (BPH). Treatment typically includes α1-receptor antagonists such as tamsulosin, which relaxes smooth muscle in the bladder neck, and 5α-reductase inhibitors like finasteride and dutasteride, which reduce prostate enlargement. Clinical trials ...