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  2. Cholinergic crisis - Wikipedia

    en.wikipedia.org/wiki/Cholinergic_crisis

    As a result of cholinergic crisis, the muscles stop responding to the high synaptic levels of acetylcholine, leading to flaccid paralysis, respiratory failure, and other signs and symptoms reminiscent of organophosphate poisoning. Other symptoms include increased sweating, salivation, bronchial secretions along with miosis (constricted pupils).

  3. What steps to take if you are diagnosed with Alzheimer's disease

    www.aol.com/steps-diagnosed-alzheimers-disease...

    Cholinesterase inhibitors (Aricept, Razadyne, Exelon): One major cause of Alzheimer's symptoms is decreased production of acetylcholine in the brain, a chemical messenger key to judgment, thought ...

  4. Alzheimer's disease - Wikipedia

    en.wikipedia.org/wiki/Alzheimer's_disease

    The first symptoms are often mistakenly attributed to aging or stress. [34] Detailed neuropsychological testing can reveal mild cognitive difficulties up to eight years before a person fulfills the clinical criteria for diagnosis of Alzheimer's disease. [35] These early symptoms can affect the most complex activities of daily living. [36]

  5. Acetylcholine - Wikipedia

    en.wikipedia.org/wiki/Acetylcholine

    Acetylcholine is a choline molecule that has been acetylated at the oxygen atom. Because of the charged ammonium group, acetylcholine does not penetrate lipid membranes. . Because of this, when the molecule is introduced externally, it remains in the extracellular space and at present it is considered that the molecule does not pass through the blood–brain

  6. Cholinergic neuron - Wikipedia

    en.wikipedia.org/wiki/Cholinergic_neuron

    A cholinergic neuron is a nerve cell which mainly uses the neurotransmitter acetylcholine (ACh) to send its messages. Many neurological systems are cholinergic.Cholinergic neurons provide the primary source of acetylcholine to the cerebral cortex, and promote cortical activation during both wakefulness and rapid eye movement sleep. [1]

  7. Neurodegenerative disease - Wikipedia

    en.wikipedia.org/wiki/Neurodegenerative_disease

    Batten disease diagnosis depends on a conflation of many criteria: clinical signs and symptoms, evaluations of the eye, electroencephalograms (EEG), and brain magnetic resonance imaging (MRI) results. [48] The diagnosis provided by these results are corroborated by genetic and biochemical testing. [48]