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Famotidine, sold under the brand name Pepcid among others, is a histamine H 2 receptor antagonist medication that decreases stomach acid production. [4] It is used to treat peptic ulcer disease, gastroesophageal reflux disease, and Zollinger-Ellison syndrome. [4] It is taken by mouth or by injection into a vein. [4] It begins working within an ...
Proton-pump inhibitors are named using the suffix "-prazole". There is a purported correlation (but no proven causal link) between the use of PPIs and the risk of dementia. [ 6 ] However, this remain controversial as chronic and co-morbid pathology, and resultant polypharmacy (including increased consumption of PPIs), will probably itself also ...
1st week: PPI (standard dose) and amoxicillin 1 g bid 2nd week: PPI (standard dose), amoxicillin 1 g, metronidazole 0.5 g and clarithromycin 0.5 g bid First line therapy Bismuth-containing quadruple therapy 10–14 PPI (standard dose) bid, tetracycline 0.5 g qid, metronidazole 0.25 g qid and bismuth standard dose qid First line or second line ...
H 2 antagonists can be used in the treatment of dyspepsia, peptic ulcers and gastroesophageal reflux disease. They have been surpassed by proton pump inhibitors (PPIs). The PPI omeprazole was found to be more effective at both healing and alleviating symptoms of ulcers and reflux oesophagitis than the H 2 blockers ranitidine and cimetidine. [2]
In 1972, functional antagonists to the H2 receptor emerged. This class of agents has since revolutionized the treatment of PUD, and its priority in the treatment of acid-related diseases has only been surpassed by the development of PPIs. Cimetidine, ranitidine, famotidine, and nizatidine are the four most commonly used H2-receptor antagonists ...
Specialty professional organizations recommend that people take the lowest effective PPI dose to achieve the desired therapeutic result when used to treat gastroesophageal reflux disease long-term. [ 20 ] [ 21 ] [ 22 ] In the United States, the Food and Drug Administration (FDA) has advised that over-the-counter PPIs, such as Prilosec OTC ...