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Wetting solution molecules break the intermolecular forces between each molecule in the organic phase and each water molecule in the aqueous phase by displacement. [5] Due to the lowered attractive forces, the surface tension is reduced. Upon adding more wetting solution, the elevated concentration of wetting solution molecules leads to a ...
The thirteenth edition authors received three-million dollars from pharmaceutical companies which was undisclosed. Unlike earlier editions which were praised for being up to date, [4] an analysis of the 13th edition found that the citations were older than those of other pharmacology textbooks. [9]
In pharmacology, clearance is a pharmacokinetic parameter representing the efficiency of drug elimination. This is the rate of elimination of a substance divided by its concentration. [1]
When these values are exceeded, the displacement of the contact line, such as the one in Figure 3, will take place by either expansion or retraction of the droplet. [31] Figure 6 depicts the advancing and receding contact angles. The advancing contact angle is the maximum stable angle, whereas the receding contact angle is the minimum stable angle.
Values for other compounds may be found in a variety of available reviews and monographs. [ 2 ] : 551ff [ 21 ] [ page needed ] [ 22 ] : 1121ff [ 23 ] [ page needed ] [ 24 ] Critical discussions of the challenges of measurement of log P and related computation of its estimated values (see below) appear in several reviews.
Martindale: The Complete Drug Reference is a reference book published by Pharmaceutical Press listing some 6,000 drugs and medicines used throughout the world, including details of over 125,000 proprietary preparations. It also includes almost 700 disease treatment reviews.
In the field of pharmacokinetics, the area under the curve (AUC) is the definite integral of the concentration of a drug in blood plasma as a function of time (this can be done using liquid chromatography–mass spectrometry [1]).
The Carr index (Carr's index [1] or Carr's Compressibility Index [2]) is an indicator of the compressibility of a powder.It is named after the scientist Ralph J. Carr, Jr. The Carr index is calculated by the formula =, where is the freely settled bulk density of the powder, and is the tapped bulk density of the powder after "tapping down".