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Intensity modulated radiation therapy (IMRT) is an advanced radiotherapy technique used to minimize the amount of normal tissue being irradiated in the treatment field. In some systems, this intensity modulation is achieved by moving the leaves in the MLC during the course of treatment, thereby delivering a radiation field with a non-uniform (i ...
The inaugural CyberKnife system was installed at Stanford University in 1991, receiving clearance for clinical investigation by the U.S. Food and Drug Administration (FDA) in 1994. Following extensive clinical research, the FDA granted approval for the treatment of intracranial tumors in 1999 and for tumors throughout the body in 2001 ...
The success of this first unit led to the construction of a second device, containing 179 cobalt-60 sources. This second Gamma Knife unit was designed to produce spherical lesions to treat brain tumors and intracranial arteriovenous malformations (AVMs). [9] Additional units were installed in the 1980s all with 201 cobalt-60 sources. [10]
Radionuclide therapy (also known as systemic radioisotope therapy, radiopharmaceutical therapy, or molecular radiotherapy), is a form of targeted therapy. Targeting can be due to the chemical properties of the isotope such as radioiodine which is specifically absorbed by the thyroid gland a thousandfold better than other bodily organs.
[6] [7] In 2011, Accuray completed its $277 million acquisition of TomoTherapy Inc., creator of advanced radiation therapy solutions for cancer care. [8] In 2012, the company acquired Morphormics for a total $5.7 million. Morphormics was founded by University of North Carolina at Chapel Hill faculty and specialized in developing imaging software.
The Gamma Knife relied on a stereotactic frame screwed into the patient's skull as an external surrogate to triangulate the location of the subject's tumor; Adler instead wanted to rely on recent medical imaging advancements and internal anatomical structures to guide the beam. Dr. Adler also sought to eliminate the costs to secure and ...
SPECT image (bone tracer) of a mouse MIP Collimator used to collimate gamma rays (red arrows) in a gamma camera. Single-photon emission computed tomography (SPECT, or less commonly, SPET) is a nuclear medicine tomographic imaging technique using gamma rays. [1]
These studies are comparative, noting differences between patients receiving a new device versus patients that receive spinal fusion or another previously-approved disc replacement. The below table illustrates currently-approved disc replacement devices, their approval dates, the number of approved levels for each device, and their current ...