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Platybasia; Specialty: Neurosurgical, orthopedic: Symptoms: Platybasia is characterised by abnormal flattening of the skull base as defined as a base of skull angle over 143º.In the absence of neural compression, pain at the back of the skull and upper part of the neck is the most common symptom.
Potentially life-threatening complications, all of which become more common in more severe OI, include: tearing of the major arteries, such as the aorta; [1]: 333 [11] pulmonary valve insufficiency secondary to distortion of the ribcage; [1]: 335–341 [12] and basilar invagination. [13]: 106–107
Basilar invagination is invagination (infolding) of the base of the skull that occurs when the top of the C2 vertebra migrates upward. It can cause narrowing of the foramen magnum (the opening in the skull where the spinal cord passes through to the brain). It also may press on the lower brainstem. [1]
Life expectancy is generally normal. [3] It affects about one per million people. [1] Males and females are equally commonly affected. [5] Modern descriptions of the condition date to at least 1896. [6] The term is from cleido 'collarbone', cranial from Greek κρανίο 'skull', and dysostosis 'formation of abnormal bone'. [7]
The distances between the dens and surrounding structures are also key features that can suggest the diagnosis, with the normal distance between the dens and basion (i.e., dens–basion interval; BDI) measuring less than 9 mm on CT, and the distance between the atlas and dens (i.e., atlas–dens interval; ADI) measuring less than 3 mm on CT, although this can be increased in cases of ...
Corticobasal degeneration (CBD) is a rare neurodegenerative disease involving the cerebral cortex and the basal ganglia. [1] CBD symptoms typically begin in people from 50 to 70 years of age, and typical survival before death is eight years.
Invagination can be driven by a number of mechanisms at the cellular level. Regardless of the force-generating mechanism that causes the bending of the epithelium, most instances of invagination result in a stereotypical cell shape change.
Scaphocephaly or sagittal craniosynostosis is a type of cephalic disorder which occurs when there is a premature fusion of the sagittal suture.Premature closure results in limited lateral expansion of the skull, resulting in a characteristic long, narrow head. [1]