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Mebendazole (MBZ), sold under the brand name Vermox among others, is a medication used to treat a number of parasitic worm infestations. [5] This includes ascariasis , pinworm infection , hookworm infections , guinea worm infections and hydatid disease , among others. [ 5 ]
Mebendazole (for most nematode infections) Pyrantel pamoate (for most nematode infections) Thiabendazole (for roundworm infections) Diethylcarbamazine (for treatment of Lymphatic filariasis) Ivermectin (for prevention of river blindness) Fenbendazole
Pinworm infection (threadworm infection in the UK), also known as enterobiasis, is a human parasitic disease caused by the pinworm, Enterobius vermicularis. [3] The most common symptom is pruritus ani, or itching in the anal area. [1]
Pyrantel is a medication used to treat a number of parasitic worm infections. [2] This includes ascariasis, hookworm infections, enterobiasis (pinworm infection), trichostrongyliasis, and trichinellosis. [2]
A 2008 review found that the efficacy of single-dose treatments for hookworm infections were as follows: 72% for albendazole, 15% for mebendazole, and 31% for pyrantel pamoate. [29] This substantiates prior claims that albendazole is much more effective than mebendazole for hookworm infections.
The substance appears to have a slight toxicity in higher doses, with effects such as liver and intestinal disorders at high exposure in test animals (just below LD 50 level). [citation needed] Some reproductive disorders and decreasing weaning weight have been observed, also at high exposure. Effects on humans from use as a drug include nausea ...
Flubendazole is an anthelmintic, used both in humans and for veterinarian purposes. It is very close chemically to mebendazole , the only difference being an added fluorine atom. [ 2 ]
This is a particularly serious problem in helminth parasites of small ruminant farm animals. [12] There are many factors that contribute to anthelmintic resistance, such as frequent, mass anthelmintic treatment, underdosing, treating repeatedly with only one anthelmintic, and resistance being transmitted during transfer of animals. [ 12 ]