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  2. Nonsteroidal anti-inflammatory drug - Wikipedia

    en.wikipedia.org/wiki/Nonsteroidal_anti...

    Kidney failure is especially a risk if the patient is also concomitantly taking an ACE inhibitor (which removes angiotensin II's vasoconstriction of the efferent arteriole) and a diuretic (which drops plasma volume, and thereby RPF)—the so-called "triple whammy" effect. [82] In rarer instances NSAIDs may also cause more severe kidney ...

  3. Analgesic nephropathy - Wikipedia

    en.wikipedia.org/wiki/Analgesic_nephropathy

    NSAIDs caused no adverse effects on renal function in healthy dogs subjected to anesthesia. [11] [12] [13] Most healthy kidneys contain enough physiologic reserve to compensate for this NSAID-induced decrease in blood flow. However, those subjected to additional injury from phenacetin or paracetamol may progress to analgesic nephropathy.

  4. Sulindac - Wikipedia

    en.wikipedia.org/wiki/Sulindac

    Like other NSAIDs, it is useful in the treatment of acute or chronic inflammatory conditions. Sulindac is a prodrug, derived from sulfinylindene, that is converted in the body to the active NSAID. More specifically, the agent is converted by liver enzymes to a sulfide that is excreted in the bile and then reabsorbed from the intestine.

  5. Anti-inflammatory - Wikipedia

    en.wikipedia.org/wiki/Anti-inflammatory

    In whole, the NSAIDs prevent the prostaglandins from ever being synthesized, reducing or eliminating the inflammation and resulting pain. [citation needed] Some common examples of NSAIDs are aspirin, ibuprofen, and naproxen. The newer specific COX-inhibitors are not classified together with the traditional NSAIDs, even though they presumably ...

  6. Prostaglandin inhibitors - Wikipedia

    en.wikipedia.org/wiki/Prostaglandin_inhibitors

    Prostaglandin inhibitors are drugs that inhibit the synthesis of prostaglandin in human body. [1] There are various types of prostaglandins responsible for different physiological reactions such as maintaining the blood flow in stomach and kidney, regulating the contraction of involuntary muscles and blood vessels, and act as a mediator of inflammation and pain.

  7. Diflunisal - Wikipedia

    en.wikipedia.org/wiki/Diflunisal

    In October 2020, the U.S. Food and Drug Administration (FDA) required the drug label to be updated for all nonsteroidal anti-inflammatory medications to describe the risk of kidney problems in unborn babies that result in low amniotic fluid. [15] [16] They recommend avoiding NSAIDs in pregnant women at 20 weeks or later in pregnancy. [15] [16]

  8. This woman's powerful photo shows the painful reality of ...

    www.aol.com/news/2015-10-28-this-womans-powerful...

    The important reason Jenn Alter shared her real breast cancer pictures. https: ... pain, bald heads, burnt skin, and broken hearts. If this doesn't make you "aware" then I don't know what will.

  9. Nabumetone - Wikipedia

    en.wikipedia.org/wiki/Nabumetone

    Nabumetone has little effect on renal prostaglandin secretion and less of an association with heart failure than other traditional drugs of the class. [9] Effects of nabumetone on blood pressure control in hypertensive patients on ACE inhibitors are also good, [clarification needed] equivalent to paracetamol. [10]