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The preferred treatment for those under the age of 65 is high-dose chemotherapy, commonly with bortezomib-based regimens, and lenalidomide–dexamethasone, [106] to be followed by a stem cell transplant. A 2016 study concluded that stem cell transplant is the preferred treatment for multiple myeloma. [107]
Isatuximab, sold under the brand name Sarclisa, is a monoclonal antibody (mAb) medication for the treatment of multiple myeloma. [6] [4]The most common side effects include neutropenia (low levels of neutrophils, a type of white blood cell), infusion reactions, pneumonia (infection of the lungs), upper respiratory tract infection (such as nose and throat infections), diarrhoea and bronchitis ...
Lenalidomide, sold under the brand name Revlimid among others, is a medication used to treat multiple myeloma, smoldering myeloma, and myelodysplastic syndromes (MDS). [8] For multiple myeloma, it is a first line treatment, and is given with dexamethasone. [8] It is taken by mouth. [8]
Ixazomib (trade name Ninlaro) is a drug for the treatment of multiple myeloma, [5] a type of white blood cell cancer, [6] in combination with other drugs. It is taken by mouth in the form of capsules. Common side effects include diarrhea, constipation and low platelet count.
Elranatamab, sold under the brand name Elrexfio, is a medication used for the treatment of multiple myeloma. [8] [12] Elranatamab is a bispecific B-cell maturation antigen (BCMA)-directed CD3 T-cell engager. [8] [12] [13] [14] Elranatamab is given by subcutaneous injection. [8] [12]
Eligible participants were required to have newly diagnosed multiple myeloma and were ineligible for transplant. [2] Efficacy of daratumumab and hyaluronidase-fihj in combination with Rd (D-Rd) was evaluated in a single-arm cohort of this trial. [2] Eligible participants had received at least one prior line of therapy.
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