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Ileitis is an inflammation of the ileum, a portion of the small intestine. Mycobacterium tuberculosis infection may mimic Crohn's disease Ileitis. [ 1 ] Ileitis may be linked to a broad range of illnesses, such as sarcoidosis , amyloidosis , ischemia , neoplasms , spondyloarthropathies , vasculitides , drug-related conditions, and eosinophilic ...
The cause of segmental colitis associated with diverticula is unknown. Several factors may influence the development of the disease, such as local colonic ischemia, fecal stasis, or mucosal prolapse. Several factors may influence the development of the disease, such as local colonic ischemia, fecal stasis, or mucosal prolapse.
Treatment is usually started by administering drugs with high anti-inflammatory effects, such as prednisone. Once the inflammation is successfully controlled, another drug to keep the disease in remission, such as mesalazine in UC, is the main treatment. If further treatment is required, a combination of an immunosuppressive drug (such as ...
Ileitis more commonly occurs in the setting of pancolitis (occurring in 20% of cases of pancolitis), [12] and tends to correlate with the activity of colitis. This so-called "backwash ileitis" can occur in 10–20% of people with pancolitis and is believed to be of little clinical significance. [22]
Autoimmune causes of enteritis such as Crohn's disease require significant chronic treatment to avoid nutritional deficiencies, cancer, bacterial overgrowth, and other complications. [5] Some patients with mild forms of the disease may not need treatment, but a majority of people with Crohn's disease require glucocorticoid medications. [24]
While the exact cause or causes are unknown, Crohn's disease seems to be due to a combination of environmental factors and genetic predisposition. [96] Crohn's is the first genetically complex disease in which the relationship between genetic risk factors and the immune system is understood in considerable detail. [ 97 ]
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