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The structure–activity relationship (SAR) is the relationship between the chemical structure of a molecule and its biological activity. This idea was first presented by Alexander Crum Brown and Thomas Richard Fraser at least as early as 1868. [1][2] The analysis of SAR enables the determination of the chemical group responsible for evoking a ...
Tests of sufficiency in biology are used to determine if the presence of an element permits the biological phenomenon to occur. In other words, if sufficient conditions are met, the targeted event is able to take place. However, this does not mean that the absence of a sufficient biological element inhibits the biological event from occurring.
A biomolecule or biological molecule is loosely defined as a molecule produced by a living organism and essential to one or more typically biological processes. [1] Biomolecules include large macromolecules such as proteins, carbohydrates, lipids, and nucleic acids, as well as small molecules such as vitamins and hormones.
Medicinal or pharmaceutical chemistry is a scientific discipline at the intersection of chemistry and pharmacy involved with designing and developing pharmaceutical drugs. Medicinal chemistry involves the identification, synthesis and development of new chemical entities suitable for therapeutic use. It also includes the study of existing drugs ...
Interactive animation of the structure of ATP. Adenosine triphosphate (ATP) is a nucleoside triphosphate [ 2 ] that provides energy to drive and support many processes in living cells, such as muscle contraction, nerve impulse propagation, and chemical synthesis.
A protein is a polyamide. Secondary structure: regularly repeating local structures stabilized by hydrogen bonds. The most common examples are the α-helix, β-sheet and turns. Because secondary structures are local, many regions of different secondary structure can be present in the same protein molecule.
Metabolomics. The central principle of biology showing the flow of information from DNA to the phenotype. Associated with each stage is the corresponding systems biology tool, from genomics to metabolomics. Metabolomics is the scientific study of chemical processes involving metabolites, the small molecule substrates, intermediates, and ...
L-Ribose Fischer Projection. Ribose is a simple sugar and carbohydrate with molecular formula C 5 H 10 O 5 and the linear-form composition H−(C=O)−(CHOH) 4 −H. The naturally occurring form, d-ribose, is a component of the ribonucleotides from which RNA is built, and so this compound is necessary for coding, decoding, regulation and expression of genes.