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2. Tocilizumab - Wikipedia

   en.wikipedia.org/wiki/Tocilizumab

   Interleukin 6 (IL-6) is a cytokine that plays an important role in immune response and is implicated in the pathogenesis of many diseases, such as autoimmune diseases, multiple myeloma and prostate cancer. Tocilizumab was jointly developed by Osaka University and Chugai, and was licensed in 2003 by Hoffmann-La Roche. [19] Tocilizumab was ...

3. Anti-interleukin-6 - Wikipedia

   en.wikipedia.org/wiki/Anti-interleukin-6

   The first approved medication in this class, tocilizumab (Actemra), is an antibody directed against the IL6-receptor. [8] The second, siltuximab (Sylvant), is directed against IL-6 itself. [ 1 ] [ 9 ] Siltuximab is approved for treatment of human immunodeficiency virus-negative and HHV-8 -negative patients with multicentric Castleman's disease .

4. List of therapeutic monoclonal antibodies - Wikipedia

   en.wikipedia.org/wiki/List_of_therapeutic...

   See the list of FDA-approved therapeutic monoclonal antibodies in the monoclonal antibody therapy page. ... Actemra, RoActemra: mab: humanized: IL-6 receptor: Y ...

5. Interleukin 6 - Wikipedia

   en.wikipedia.org/wiki/Interleukin_6

   Interleukin 6 (IL-6) is an interleukin that acts as both a pro-inflammatory cytokine and an anti-inflammatory myokine. In humans, it is encoded by the IL6 gene. [5] In addition, osteoblasts secrete IL-6 to stimulate osteoclast formation. Smooth muscle cells in the tunica media of many blood vessels also produce IL-6 as a pro-inflammatory cytokine.

6. Interleukin-6 receptor - Wikipedia

   en.wikipedia.org/wiki/Interleukin-6_receptor

   Interleukin 6 (IL6) is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in immune response. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer.

7. Nearly half of parents are going into debt over Christmas gifts

   www.aol.com/nearly-half-parents-going-debt...

   A new poll shows that 49% of parents will go into debt to buy Christmas gifts this holiday season, according to a new survey from CouponBirds.. The poll of 2,500 American adults showed that ...