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Terbinafine is an antifungal medication used to treat pityriasis versicolor, fungal nail infections, and ringworm including jock itch and athlete's foot. [1] [2] [3] It is either taken by mouth or applied to the skin as a cream or ointment.
Efinaconazole, sold under the brand name Jublia among others, is a triazole antifungal medication. It is approved for use in the United States, Canada, and Japan as a 10% topical solution for the treatment of onychomycosis (fungal infection of the nail). [3] [4] Efinaconazole acts as a 14α-demethylase inhibitor. [5] [2]
Fosravuconazole (trade name Nailin) is a triazole antifungal agent. [1] [2] In Japan, it is approved for the treatment of onychomycosis, a fungal infection of the nail. [3]It is a prodrug that is converted into ravuconazole.
An antifungal medication, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis (thrush), serious systemic infections such as cryptococcal meningitis, and others.
First topical terbinafine medication (MOB-015) was launched in February 2024 in Sweden under the name Terclara. This medication recorded 76% mycological cure rate in two phase 3 studies. The topical property of this medication ensures that typical terbinafine side effects are not present (1000 times lower terbinafine levels in plasma).
Tavaborole, sold under the brand name Kerydin, is a topical antifungal medication for the treatment of onychomycosis, a fungal infection of the nail and nail bed with a complete clearance rate of 6-7% and partial clearance rate of 23-24% in individuals whose “infection border does not reach the cuticle at the base of the large toenail.” [1] Tavaborole was approved by the US FDA in July ...