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S. epidermidis is a particular concern for people with catheters or other surgical implants because it is known to form biofilms that grow on these devices. [5] Being part of the normal skin microbiota, S. epidermidis is a frequent contaminant of specimens sent to the diagnostic laboratory.
Dispersin B may be useful for treating and preventing biofilm-associated infections caused by poly-N-acetylglucosamine-producing bacteria. Dispersin B prevented the formation of S. epidermidis biofilm, which suggests that biofilm-releasing enzymes can exhibit broad-spectrum activity and could be potential antibiofilm agents. [16]
The aggregation of α-type PSMs into fibrils is able to modulate S. aureus biofilm formation. [13] In vitro measurement of PSMβ expression in S. epidermidis has shown to be increased in biofilm as opposed to planktonic growth, suggesting a link between PSMβ and biofilm formation. [2]
The S. haemolyticus strain JCSC1435 genome contains a 2,685,015 bp chromosome and three plasmids of 2,300 bp, 2,366 bp, and 8,180 bp. The chromosome is comparable in size to those of S. aureus and S. epidermidis and contains a similar G+C content. In addition, a large proportion of the open reading frames (ORFs) are conserved across all three ...
Starting very early, research into biofilm formation in Staphylococcus epidermidis has served as a model for other staphylococci such as Staphylococcus aureus and other CoNS species. Moreover, data also showed that S. capitis have a strain (AYP1020) that researchers use to general genomic characteristics compared to S. epidermidis’ strain ...
S. aureus glutamyl endopeptidase GluV8 [1] The first discovered enzyme of this family, and the most well characterized, was isolated from the Staphylococcus aureus strain V8, and hence better known as "V8 protease". Other common references to this protease are staphylococcal serine protease, and SspA from its corresponding gene. [1] [2] [3]
Potential probiotic treatment includes the use of Staphylococcus epidermidis to inhibit C. acnes growth. S. epidermidis produces succinic acid which has been shown to inhibit C. acnes growth. [42] Lactobacillus plantarum has also been shown to act as an anti-inflammatory and improve antimicrobial properties of the skin when applied topically ...
A follow-up study published in 2020 found that the eyesalve had a significant anti-biofilm effect. The remedy of combined ingredients was effective at reducing biofilms of S. epidermidis and MRSA and eradicating biofilms of S. aureus Newman, A. baumannii and S. pyogenes in an established soft-tissue wound model. [4]