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Superoxide dismutase 2, mitochondrial (SOD2), also known as manganese-dependent superoxide dismutase (MnSOD), is an enzyme which in humans is encoded by the SOD2 gene on chromosome 6. [ 5 ] [ 6 ] A related pseudogene has been identified on chromosome 1.
Irwin Fridovich and Joe McCord at Duke University discovered the enzymatic activity of superoxide dismutase in 1968. [5] SODs were previously known as a group of metalloproteins with unknown function; for example, CuZnSOD was known as erythrocuprein (or hemocuprein, or cytocuprein) or as the veterinary anti-inflammatory drug "Orgotein". [6]
Ribbon drawing of the subunit 3D structure of Cu,Zn superoxide dismutase. Irwin Fridovich (August 2, 1929 – November 2, 2019) [1] was an American biochemist who, together with his graduate student Joe M. McCord, discovered the enzymatic activity of copper-zinc superoxide dismutase (SOD), [2] [3] —to protect organisms from the toxic effects of superoxide free radicals formed as a byproduct ...
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The Ayres Thrush, formerly the Snow S-2, [1] Aero Commander Ag Commander, and Rockwell Thrush Commander, is an American agricultural aircraft produced by Ayres Corporation and more recently by Thrush Aircraft. It is one of the most successful and long-lived agricultural application aircraft types in the world, with almost 2,000 sold since the ...
Drug metabolism is the metabolic breakdown of drugs by living organisms, usually through specialized enzymatic systems. More generally, xenobiotic metabolism (from the Greek xenos "stranger" and biotic "related to living beings") is the set of metabolic pathways that modify the chemical structure of xenobiotics, which are compounds foreign to an organism's normal biochemistry, such as any drug ...
The port numbers in the range from 0 to 1023 (0 to 2 10 − 1) are the well-known ports or system ports. [3] They are used by system processes that provide widely used types of network services.