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Medications like Ozempic and Wegovy, which are used to treat type 2 diabetes and boost weight loss, may also help reduce knee osteoarthritis-related pain in people with obesity, a trial finds.
Gene augmentation, [14] gene replacement, and novel transgene gene therapy [15] strategies for the potential medical management of osteoarthritis are under preliminary research to define pathological mechanisms and possible treatments for this chronic disease. While viral vector gene therapies predominate, both viral and non-viral vectors have ...
Several approved drugs are being investigated as repurposed agents in the treatment of osteoarthritis such as liraglutide (anti-diabetic and anti-obesity drug: NCT02905864), Metformin (anti-diabetic drug: NCT04767841, NCT05034029), Zoledronic acid (anti-osteoporotic drug: NCT04303026), etc. [4] Paroxetine has been deemed to have DMOAD activity ...
In clinical studies, NGF inhibitors have demonstrated efficacy in reducing pain and improving function in persons with knee or hip osteoarthritis. [2] While injectable NGF inhibitors (anti-NGF antibodies) have demonstrated greater efficacy in pain relief compared to NSAID and opioid medications, [3] those receiving the treatment were more likely to experience rapid progression of the disease ...
Osteoarthritis is the most common type of arthritis. An estimated 595 million people worldwide had this condition in 2020 — that’s 7.6 percent of the global population!
Research conducted on horses, dogs, and cats has led to the development of stem cell treatments in veterinary medicine which can target a wide range of injuries and diseases, such as myocardial infarction, stroke, tendon and ligament damage, osteoarthritis, osteochondrosis and muscular dystrophy, both in large animals as well as in humans.