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Epinephrine, also known as adrenaline, is a medication and hormone. [10] [11] As a medication, it is used to treat several conditions, including anaphylaxis, cardiac arrest, asthma, and superficial bleeding. [8] Inhaled epinephrine may be used to improve the symptoms of croup. [12] It may also be used for asthma when other treatments are not ...
The 100 pg/mL concentration is a target considered important to achieve hemodynamic stabilization and halt the progression of anaphylaxis. The higher 9.06 mg dose sustained plasma epinephrine levels above 100 pg/mL for 2 hours post-dose, ensuring long-lasting protection.
An epinephrine autoinjector (or adrenaline autoinjector, also known by the trademark EpiPen) is a medical device for injecting a measured dose or doses of epinephrine (adrenaline) by means of autoinjector technology. It is most often used for the treatment of anaphylaxis. The first epinephrine autoinjector was brought to market in 1983.
The US Food and Drug Administration approved the first nasal spray epinephrine drug for severe allergic reactions known as anaphylaxis, providing a needle-free alternative to EpiPens and similar ...
Neffy's approval is based on four studies in 175 healthy adults without anaphylaxis that measured the epinephrine concentrations in the blood following the administration of Neffy or approved ...
Anaphylaxis occurs when the body's immune system develops a sudden, unexpected reaction to a foreign substance, such as food, ... First marketed in 1901, epinephrine predates the FDA itself ...
Anaphylactoid reaction, non-immune anaphylaxis, or pseudoanaphylaxis, is a type of anaphylaxis that does not involve an allergic reaction but is due to direct mast cell degranulation. [ 10 ] [ 42 ] Non-immune anaphylaxis is the current term, as of 2018, used by the World Allergy Organization [ 42 ] with some recommending that the old ...
The nasal spray Neffy is the first non-injectable epinephrine to treat the life-threatening allergic response EpiPen Alternative for Anaphylaxis Approved by FDA — No Needles Skip to main content