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  2. Adaptive evolution in the human genome - Wikipedia

    en.wikipedia.org/wiki/Adaptive_evolution_in_the...

    Adaptive evolution results from the propagation of advantageous mutations through positive selection. This is the modern synthesis of the process which Darwin and Wallace originally identified as the mechanism of evolution. However, in the last half century, there has been considerable debate as to whether evolutionary changes at the molecular ...

  3. Natural selection - Wikipedia

    en.wikipedia.org/wiki/Natural_selection

    The term natural selection is most often defined to operate on heritable traits, because these directly participate in evolution. However, natural selection is "blind" in the sense that changes in phenotype can give a reproductive advantage regardless of whether or not the trait is heritable.

  4. mRNA display - Wikipedia

    en.wikipedia.org/wiki/MRNA_display

    The mRNA/DNA-polypeptide fusions can be selected over immobilized selection targets for several rounds (Figure 3). There might be a relatively high background for the first few rounds of selection, and this can be minimized by increasing selection stringency, such as adjusting salt concentration, amount of detergent, and/or temperature during ...

  5. Molecular evolution - Wikipedia

    en.wikipedia.org/wiki/Molecular_evolution

    Selection can occur when an allele confers greater fitness, i.e. greater ability to survive or reproduce, on the average individual than carries it. A selectionist approach emphasizes e.g. that biases in codon usage are due at least in part to the ability of even weak selection to shape molecular evolution.

  6. Site-specific recombinase technology - Wikipedia

    en.wikipedia.org/wiki/Site-specific_recombinase...

    These two families can mediate up to three types of DNA rearrangements (integration, excision/resolution, and inversion) along different reaction routes based on their origin and architecture. [5] Tyr- and Ser-SSRs from prokaryotes (phages; grey) and eukaryotes (yeasts; brown); a comprehensive overview (including references) can be found in. [6]

  7. Soft selective sweep - Wikipedia

    en.wikipedia.org/wiki/Soft_selective_sweep

    Overview of two soft selective sweep models (Jensen, J., 2014). A selective sweep occurs when, due to strong positive natural selection, beneficial alleles quickly go to fixation in a population and results in the reduction or elimination of variation among the nucleotides near that allele. [7]

  8. Genetic engineering - Wikipedia

    en.wikipedia.org/wiki/Genetic_engineering

    This is an accepted version of this page This is the latest accepted revision, reviewed on 19 January 2025. Manipulation of an organism's genome For a non-technical introduction to the topic of genetics, see Introduction to genetics. For the song by Orchestral Manoeuvres in the Dark, see Genetic Engineering (song). For the Montreal hardcore band, see Genetic Control. Part of a series on ...

  9. Baldwin effect - Wikipedia

    en.wikipedia.org/wiki/Baldwin_effect

    James Mark Baldwin and others suggested that an organism's ability to learn new behaviours (e.g. to acclimatise to a new stressor) will affect its reproductive success and will therefore have an effect on the genetic makeup of its species through natural selection. It posits that subsequent selection might reinforce the originally learned ...