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Since the 2010s, oxybutynin has increasingly been used to treat hyperhidrosis (excessive sweating). [15] [16] Numerous studies have identified concrete benefits of the drug in treating this condition, but have not identified appropriate dosing or the full spectrum of possible side effects, although dry mouth is seemingly infrequent in patients with hyperhidrosis.
Hyperhidrosis is a medical condition in which a person exhibits excessive sweating, [1] [2] more than is required for the regulation of body temperature. [3] Although it is primarily a physical burden, hyperhidrosis can deteriorate the quality of life of the people who are affected from a psychological, emotional, and social perspective. [4]
Focal hyperhidrosis, also known as primary hyperhidrosis, is a disease characterized by an excessive sweating localized in certain body regions (particularly palms, feet and underarms). Studies suggest that this condition, affecting between 1% and 3% of the US population, seems to have a genetic predisposition in about two thirds of those affected.
Glycopyrronium tosylate, sold under the brand name Qbrexza among others, is a medication used for the treatment of primary axillary hyperhidrosis. [ 1 ] [ 2 ] [ 3 ] It was approved for medical use in the United States in June 2018, [ 4 ] and in Japan in January 2022.
Night sweats or nocturnal hyperhidrosis [1] is the repeated occurrence of excessive sweating during sleep. [2] The person may or may not also perspire excessively while awake. One of the most common causes of night sweats in women over 40 is the hormonal changes related to menopause and perimenopause . [ 3 ]
Palmoplantar hyperhidrosis is excessive sweating localized to the palms of the hands and soles of the feet. It is a form of focal hyperhidrosis in that the excessive sweating is limited to a specific region of the body. As with other types of focal hyperhidrosis (e.g. axillary and craniofacial) the sweating tends to worsen during warm weather. [1]
The Minor test can be used as a diagnostic tool to evaluate underactive (hypohidrosis) [4] and overactive (hyperhidrosis) sweating. This test can also reveal Horner's syndrome . [ 2 ]
Compensatory hyperhidrosis; Following Endoscopic thoracic sympathectomy surgery for axillary (armpit), palmar (palm) hyperhidrosis and blushing, the body may sweat excessively at untreated areas, most commonly the lower back and trunk, but can be spread over the total body surface below the level of the cut.