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TRIzol reagent contains guanidinium thiocyanate and phenol.. TRIzol is a widely used [1] chemical solution used in the extraction of DNA, RNA, and proteins from cells. The solution was initially used and published by Piotr Chomczyński and Nicoletta Sacchi in 1987.
Chemical & Engineering News publishes an annual list of the world's largest chemical producers by sales, excluding formulated products such as pharmaceutical drugs and coatings. [1] In 2018, sales of the top fifty companies amounted to US$ 951,000,000,000, an increase of 11.8% compared to the top fifty producers of 2017. [ 2 ]
VWR International is an American company involved in the distribution of research laboratory products, with over 1,200,000 items to more than 250,000 customers in North America and Europe. The U.S. division is headquartered in Radnor, Pennsylvania .
1,2,4-Triazole (as ligand in coordination compounds, Htrz abbreviation is sometimes used) is one of a pair of isomeric chemical compounds with molecular formula C 2 H 3 N 3, called triazoles, which have a five-membered ring of two carbon atoms and three nitrogen atoms. 1,2,4-Triazole and its derivatives find use in a wide variety of applications.
Other denaturing chemicals such as 2-mercaptoethanol and sarcosine may also be used. The major downside is that phenol and chloroform are both hazardous and inconvenient materials, and the extraction is often laborious, so in recent years many companies now offer alternative ways to isolate RNA.
Univar Solutions Inc.(formerly Royal Vopak) is a global chemical and ingredients distributor and provider of value-added services.. Founded in 1924 as Van Waters & Rogers, it was acquired in August 2023 by funds controlled by Apollo Global Management. [2]