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Breast cancer is the most common cancer in women worldwide, and can, rarely, also occur in men. There are many different types of breast cancer, of which triple-negative breast cancer is one of ...
Triple-negative breast cancer comprises 15–20% of all breast cancer cases [3] and affects more young women or women with a mutation in the BRCA1 gene than other breast cancers. [4] Triple-negative breast cancers comprise a very heterogeneous group of cancers. TNBC is the most challenging breast cancer type to treat. [5]
3. "The current standard for treating patients with clinical stage 2 or 3 triple-negative breast cancer is to administer chemotherapy in addition to immunotherapy prior to surgery. This ...
Sacituzumab govitecan is indicated for the treatment of adults with metastatic triple-negative breast cancer who received at least two prior therapies for metastatic disease; [11] people with unresectable locally advanced or metastatic triple-negative breast cancer (mTNBC) who have received two or more prior systemic therapies, at least one of them for metastatic disease; [14] and for people ...
Triple-negative breast cancer acts aggressively, grows quickly, spreads further and is more likely to return, the American Cancer Society says. It often occurs in women younger than 40, Black ...
Staging breast cancer is the initial step to help physicians determine the most appropriate course of treatment. As of 2016, guidelines incorporated biologic factors, such as tumor grade, cellular proliferation rate, estrogen and progesterone receptor expression, human epidermal growth factor 2 (HER2) expression, and gene expression profiling into the staging system.
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