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In September 2001, the United States Food and Drug Administration (FDA) sent a warning letter to the CEO of Merck, stating, "Your promotional campaign discounts the fact that in the VIGOR study, patients on Vioxx were observed to have a four to five fold increase in myocardial infarctions (MIs) compared to patients on the comparator ...
June. John Deutch. Sometime in June, a walk-in agent for People's Republic of China intelligence services approached the United States Central Intelligence Agency (CIA) office in Taiwan and provided them with an official PRC document classified "Secret" that contained design information of all seven of America's nuclear warheads. [1]
U.S. Representative Chris Cox (Republican-California) chaired the Committee that produced the report. The Report of the Select Committee on U.S. National Security and Military/Commercial Concerns with the People's Republic of China, commonly known as the Cox Report after Representative Christopher Cox, is a classified U.S. government document reporting on the People's Republic of China's ...
The therapeutic recommended dosages were 12.5, 25, and 50 mg with an approximate bioavailability of 93%. [12] [13] [14] Rofecoxib crossed the placenta and blood–brain barrier, [12] [13] [15] and took 1–3 hours to reach peak plasma concentration with an effective half-life (based on steady-state levels) around 17 hours.
Jetstar Boeing 787 fact sheet. A factsheet or fact sheet, also called fact file, is a single-page document containing essential information about a product, substance, service or other topic. Factsheets are frequently used to provide information to an end user, consumer or member of the public in concise, simple language. They generally contain ...
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