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Prostate cancer is the most diagnosed cancer in men in over half of the world's countries, and the leading cause of cancer death in men in around a quarter of countries. [91] Prostate cancer is rare in those under 40 years old, [92] and most cases occur in those over 60 years, [2] with the average person diagnosed at 67. [93]
One in eight men will be diagnosed with prostate cancer in their lifetime, with around 52,000 diagnoses in the UK each year (144 a day).
A histopathologic diagnosis of prostate cancer is the discernment of whether there is a cancer in the prostate, as well as specifying any subdiagnosis of prostate cancer if possible. The histopathologic subdiagnosis of prostate cancer has implications for the possibility and methodology of any subsequent Gleason scoring. [1]
MRI changes could speed-up prostate cancer diagnosis. Storm Newton, Health Reporter. October 12, 2023 at 10:00 AM.
The histopathologic diagnosis of prostate cancer has implications for the possibility and methodology of Gleason scoring. [3] For example, it is not recommended in signet-ring adenocarcinoma or urothelial carcinoma of the prostate, and the scoring should discount the foamy cytoplasms seen in foamy gland carcinoma. [3]
Molecular analysis has shown that high grade PIN and prostate cancer share many genetic abnormalities. [5] The risk for men with high grade PIN of being diagnosed with prostate cancer after repeat biopsy has decreased since the introduction of biopsies at more than six locations (traditional sextant biopsies). [3]
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