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In dogs, autoimmune skin diseases are usually not detected until visible symptoms appear, which differs from detection in humans who are able to verbally express their concerns. [2] Genetics , nutrition, and external environmental factors all collectively contribute to increasing the probability an autoimmune skin disease occurring. [ 3 ]
A dermatofibroma, or benign fibrous histiocytomas, is a benign nodule in the skin, typically on the legs, elbows or chest of an adult. [3] It is usually painless. [3] It usually ranges from 0.2cm to 2cm in size but larger examples have been reported. [3] It typically results from mild trauma such as an insect bite. [3]
The cause of fibroadenoma is unknown . [6] A connection between fibroadenomas and reproductive hormones has been suggested which may explain why they present themselves during reproductive years, increase in size during pregnancy, and regress post-menopause. [6]
Skin disorders are among the most common health problems in dogs, and have many causes. The condition of a dog's skin and coat is also an important indicator of its general health. Skin disorders of dogs vary from acute, self-limiting problems to chronic or long-lasting problems requiring life-time treatment. Skin disorders may be primary or ...
Juvenile hyaline fibromatosis (also known as fibromatosis hyalinica multiplex juvenilis [2] and Murray–Puretic–Drescher syndrome [2]) is a very rare, autosomal recessive disease due to mutations in capillary morphogenesis protein-2 (CMG-2 gene).
Skin conditions resulting from errors in metabolism are caused by enzymatic defects that lead to an accumulation or deficiency of various cellular components, including, but not limited to, amino acids, carbohydrates, and lipids. [16] Acute intermittent porphyria; Adrenoleukodystrophy (Schilder's disease) Alkaptonuria
Conditions caused by mutations in or antibodies against junctional proteins found within the epidermis of the human integumentary system. Junctional protein Condition(s) Desmocollin 1: Subcorneal pustular dermatosis type of IgA pemphigus: Desmocollin 2: Arrhythmogenic right ventricular dysplasia (ARVD) Desmoglein 1: Striate palmoplantar keratoderma
Stage III - multiple skin tumors or a large tumor invading deep to the skin with or without lymph node involvement; Stage IV – a tumor with metastasis to the spleen, liver, or bone marrow, or with the presence of mast cells in the blood [10] X-rays, ultrasound, or lymph node, bone marrow, or organ biopsies may be necessary to stage the disease.