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In the US, crisaborole is indicated for topical treatment of mild to moderate atopic dermatitis in people three months of age and older. [2]In the EU, crisaborole was authorized for treatment of mild to moderate atopic dermatitis in people two years of age and older with ≤ 40% body surface area (BSA) affected.
Side effects may occur from sudden discontinuation and prolonged, continuous use can lead to skin thinning. [2] Intermittent use of topical steroids for atopic dermatitis is safe and does not cause skin thinning. [3] [4] [5]
Topical glucocorticoid phobia is a concern or fear about using topical glucocorticoids, which is commonly found among patients with atopic dermatitis and their caregivers. [29] This phenomenon has been identified in more than 15 countries globally, including Canada , France , Japan , the United Kingdom , and the United States . [ 30 ]
This is useful for maintaining control of chronic diseases. Generally a milder topical steroid or non-steroid treatment is used on the in-between days. [12] For treating atopic dermatitis, newer (second generation) corticosteroids, such as fluticasone propionate and mometasone furoate, are more effective and safer than older ones. They are also ...
Amcinonide exhibits side effects common among other corticosteroids. While these reactions are uncommon for most delivery vehicles, the use of occlusive dressings increases the likelihood of such effects. [5] These include burning, itching, skin dryness and irritation, acne/ pimples, skin atrophy, blistering, and/ or skin discoloration.
When topical steroid medication is stopped, the skin experiences redness, burning, itchiness, scabs, hot skin, swelling, stinging, hives, or oozing. This is known as topical steroid withdrawal. After the withdrawal period is over, the atopic dermatitis can cease or is less severe than it was before. [8]
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