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Valaciclovir, also spelled valacyclovir, is an antiviral medication used to treat outbreaks of herpes simplex or herpes zoster (shingles). [2] It is also used to prevent cytomegalovirus following a kidney transplant in high risk cases. [2] It is taken by mouth. [2] Common side effects include headache and vomiting. [2]
The recommended dosage for suppression therapy for recurrent outbreaks is 1,000 mg of valacyclovir once a day or 400 mg Acyclovir taken twice a day. In addition to preventing outbreaks, these medications greatly reduce the chance of infecting someone while the patient is not having an outbreak.
Shingles vaccination is the only way for adults to be protected against both shingles and postherpetic neuralgia, with two vaccines approved for use in people over age 50. [3] The zoster vaccine Shingrix provides around 90% protection from postherpetic neuralgia, and has been used in many countries since 2017.
Shingles, also known as herpes zoster or zona, [6] is a viral disease characterized by a painful skin rash with blisters in a localized area. [2] [7] Typically the rash occurs in a single, wide mark either on the left or right side of the body or face. [1] Two to four days before the rash occurs there may be tingling or local pain in the area.
Treatments with antiviral medication such as aciclovir or valaciclovir can lessen the severity of symptomatic episodes. [1] [2] Worldwide rates of either HSV-1 or HSV-2 are between 60% and 95% in adults. [4] HSV-1 is usually acquired during childhood. [1] Since there is no cure for either HSV-1 or HSV-2, rates of both inherently increase as ...
2012 (Fixed-dose combo Stribild) 2014 (single pill) 2015 ; Emtricitabine: HIV Gilead Sciences NRTI 2003 Enfuvirtide: HIV Entry inhibitor 2003 Ensitrelvir: COVID-19: Shionogi: 3C-like protease inhibitor Entecavir: HIV NRTI 2005 Etravirine (Intelence) [8] HIV NNRTI 2008 Famciclovir: Herpes Zoster: Guanosine analogue 1994 Fomivirsen: AIDS Anti ...
The two-dose Shingrix vaccine, for instance, which protects older adults against the virus that causes painful shingles, results in sore arms in 78 percent of recipients and muscle pain and ...
Prevention of herpes viruses in immunocompromised people (such as people undergoing cancer chemotherapy) [17] It has not been found to be effective against Epstein–Barr virus and its associated infectious mononucleosis. [18] Aciclovir risks causing resistance to antiviral agents, and in 1% to 10% of cases can cause unpleasant side effects. [19]