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  2. Large cell neuroendocrine carcinoma of the lung - Wikipedia

    en.wikipedia.org/wiki/Large_cell_neuroendocrine...

    Large-cell neuroendocrine carcinoma of the lung (LCNEC of the lung), or pulmonary large-cell neuroendocrine carcinoma (PLCNC), is a highly malignant neoplasm arising from transformed epithelial cells originating in tissues within the pulmonary tree. It is currently considered to be a subtype of large-cell lung carcinoma.

  3. Large-cell lung carcinoma - Wikipedia

    en.wikipedia.org/wiki/Large-cell_lung_carcinoma

    Large-cell lung carcinoma (LCLC), or large-cell carcinoma (LCC) in short, is a heterogeneous group of undifferentiated malignant neoplasms that lack the cytologic and architectural features of small cell carcinoma and glandular or squamous differentiation. [1]

  4. Pulmonary neuroendocrine tumor - Wikipedia

    en.wikipedia.org/wiki/Pulmonary_neuroendocrine_tumor

    Small cell lung cancer (SCLC) Large cell neuroendocrine carcinoma (LCNEC of the lung) Low-grade nodular neuroendocrine proliferations ≥ 0.5 cm are classified as carcinoid tumors and smaller ones are called pulmonary tumorlets. When neuroendocrine cell hyperplasia and tumorlets are extensive, they represent the rare preinvasive lesion for ...

  5. Large-cell lung carcinoma with rhabdoid phenotype - Wikipedia

    en.wikipedia.org/wiki/Large-cell_lung_carcinoma...

    Lung cancers are now considered a large and extremely heterogeneous family of neoplasms [4] that feature widely varying genetic, biological, and clinical characteristics. . About 50 different lung cancer variants are recognized under the 2004 revision of the World Health Organization ("WHO-2004") histological typing system, the most widely recognized and used lung cancer classification sche

  6. Treatment of lung cancer - Wikipedia

    en.wikipedia.org/wiki/Treatment_of_lung_cancer

    Non-small cell lung cancer (NSCLC) cells expressing programmed death-ligand 1 (PD-L1) could interact with programmed death receptor 1 (PD-1) expressed on the surface of T cells, and result in decreased tumor cell kill by the immune system. Atezolizumab is an anti PD-L1 monoclonal antibody.

  7. Neuroendocrine tumor - Wikipedia

    en.wikipedia.org/wiki/Neuroendocrine_tumor

    Lung and thymic neuroendocrine neoplasms are classified in a similar manner, including typical and atypical carcinoids, small cell and large cell neuroendocrine carincomas. [ 7 ] Furthermore, the 2022 WHO classification introduces a two-tiered grading system for medullary thyroid carcinomas based on mitotic count, Ki-67 index and the absence or ...

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