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Mepacrine, also called quinacrine or by the trade names Atabrine or Atebrin, is a medication with several uses. It is related to chloroquine and mefloquine . Although available from compounding pharmacies , as of August 2020 approved formulations are not available in the United States.
Tafenoquine, sold under the brand name Krintafel among others, is a medication used to prevent and to treat malaria. [3] With respect to acute malaria, it is used together with other medications to prevent relapse by Plasmodium vivax. [3]
4-Aminoquinoline is a form of aminoquinoline with the amino group at the 4-position of the quinoline. The compound has been used as a precursor for the synthesis of its derivatives. [1] A variety of derivatives of 4-aminoquinoline are antimalarial agents useful in treating erythrocytic plasmodial infections. [2]
The availability of quinine for treatment had been said to be the prime reason Africa ceased to be known as the "white man's grave". A historian said, "it was quinine's efficacy that gave colonists fresh opportunities to swarm into the Gold Coast , Nigeria and other parts of west Africa".
The derivatives primaquine, tafenoquine and pamaquine have been tested for anti-malaria activity. [3] [4] Primaquine is still used routinely worldwide as part of the treatment of Plasmodium vivax and Plasmodium ovale malaria, although how it prevents malarial recurrences is not, at present, clear. [5]
A paraphyletic group, protozoans have little in common with each other. For example, Entamoeba histolytica, a unikont eukaryotic organism, is more closely related to Homo sapiens (humans), which also belongs to the unikont phylogenetic group, than it is to Naegleria fowleri, a "protozoan" bikont.
It started to acquire Baxter Healthcare Corporation's US generic injectables business, Multi-Source Injectables or MSI, and completed the transaction in May 2011. [ 7 ] In October 2011, Hikma Pharmaceuticals entered the Moroccan market through the acquisition of Promopharm, the ninth largest pharmaceutical manufacturer in Morocco. [ 8 ]
Quinoline alkaloids are naturally occurring chemical compounds from the group of alkaloids, which are chemically derived from quinoline. Some quinoline alkaloids show antiseptic , convulsive or antineoplastic effects.