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Type 2 myocardial Infarctions (T2MI) result any time coronary flow is reduced secondary to a non-thrombotic cause. Because coronary flow is determined partly by coronary perfusion pressure, a reduction in CPP increases the risk of T2MI. Reduced CPP can be the result of a multitude of pathologies including cardiogenic shock and tachyarrythmia.
In medicine, the mean arterial pressure (MAP) is an average calculated blood pressure in an individual during a single cardiac cycle. [1] Although methods of estimating MAP vary, a common calculation is to take one-third of the pulse pressure (the difference between the systolic and diastolic pressures), and add that amount to the diastolic pressure.
Pulmonary pulse pressure is normally much lower than systemic blood pressure due to the higher compliance of the pulmonary system compared to the arterial circulation. [6] It is measured by right heart catheterization or may be estimated by transthoracic echocardiography. Normal pulmonary artery pressure is 8 mmHg–20 mmHg at rest. [7]
Cardiac index is a critical parameter in evaluating cardiac performance and the adequacy of tissue perfusion. In healthy adults, the normal range of cardiac index is generally between 2.6 to 4.2 L/min/m². Values below this range may indicate hypoperfusion and are often seen in conditions such as heart failure, hypovolemia, and cardiogenic shock.
The increased risk also exists even in cases in which diastolic pressure decreases over time while systolic remains steady. [55] [54] A meta-analysis in 2000 showed that a 10 mmHg increase in pulse pressure was associated with a 20% increased risk of cardiovascular mortality, and a 13% increase in risk for all coronary end points. The study ...
The coronary arteries are mainly composed of the left and right coronary arteries, both of which give off several branches, as shown in the 'coronary artery flow' figure. Coronary artery flow Aorta. Left coronary artery. Left anterior descending artery; Left circumflex artery; Posterior descending artery; Ramus or intermediate artery; Right ...
Coronary flow reserve is used in diagnostics and treatment of patients with conditions such as coronary artery disease and syndrome X. [7] In the treatment of these conditions, vasodilators are used to allow sufficient blood to flow past a stenosis, for example, and the measurement of CFR enables the efficacy of such interventions to be measured.
The relationship between arterial stiffness and pulse wave velocity was first predicted by Thomas Young in his Croonian Lecture of 1808 [11] but is generally described by the Moens–Korteweg equation [12] or the Bramwell–Hill equation. [13] Typical values of PWV in the aorta range from approximately 5 m/s to >15 m/s. [14]