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ROS, alone, cause more than 20 types of DNA damage. [50] Oxidative DNA damages cause both mutations [51] and epigenetic alterations. [52] [46] [53] RNS also cause mutagenic DNA damages. [54] A normal cell may undergo carcinogenesis to become a cancer cell if it is frequently subjected to DNA damage during long periods of chronic inflammation ...
Tendons and ligaments play an active role in maintain joint stability and controls the limits of joint movements, once injured tendons and ligaments detrimentally impact motor functions. [2] [8] Continuous exercise or movement of a musculoskeletal injury can result in chronic inflammation with progression to permanent damage or disability. [9]
Rheumatoid arthritis (RA) is a long-term autoimmune disorder that primarily affects joints. [1] It typically results in warm, swollen, and painful joints. [1] Pain and stiffness often worsen following rest. [1] Most commonly, the wrist and hands are involved, with the same joints typically involved on both sides of the body. [1]
Painful joints can have a significant impact on quality of life and the ability to do daily activities. Joint pain is a common symptom we all experience at some point or another. Painful joints ...
Research reveals that long-term inflammation may lead to conditions like insulin resistance and possibly even type 2 diabetes. Conversely, certain health conditions may increase your risk of ...
Inflammatory arthritis is a group of diseases which includes: rheumatoid arthritis, psoriatic arthropathy, inflammatory bowel disease, adult-onset Still's disease, scleroderma, juvenile idiopathic arthritis, and systemic lupus erythematosus (SLE).