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Systemic treatments of mycosis fungoides often lead to resistance; as such, additional treatment options are often necessary in advanced disease. [ 21 ] Other treatments have been suggested, however, larger and more extensive research is needed to identify effective treatment strategies for this disease. [ 5 ]
Fungal infection, also known as mycosis, is a disease caused by fungi. [ 5 ] [ 13 ] Different types are traditionally divided according to the part of the body affected; superficial, subcutaneous , and systemic.
Candidiasis is a fungal infection due to any species of the genus Candida (a yeast). [4] When it affects the mouth, in some countries it is commonly called thrush. [3] Signs and symptoms include white patches on the tongue or other areas of the mouth and throat. [3]
The presentation depends if it is mycosis fungoides or Sézary syndrome, the most common, though not the only types. Among the symptoms for the aforementioned types are: enlarged lymph nodes, an enlarged liver and spleen, and non-specific dermatitis. [1]
Sézary disease and mycosis fungoides are cutaneous T-cell lymphomas having a primary manifestation in the skin. [5] The disease's origin is a peripheral CD4+ T-lymphocyte, [ 3 ] although rarer CD8+/CD4- cases have been observed. [ 3 ]
It is also used in the treatment of certain T-cell lymphomas, particularly mycosis fungoides. [citation needed] Peginterferon alfa-2a is a long acting interferon. Interferons are proteins released in the body in response to viral infections.
Bright light therapy is a treatment method that involves exposure to a high-intensity light source that mimics natural sunlight, says Frank A. Ghinassi, Ph.D., senior vice president of Behavioral ...
Clobetasol propionate is used for the treatment of various skin disorders including eczema, herpes labialis, [16] psoriasis, and lichen sclerosus.It is also used to treat several auto-immune diseases including alopecia areata, lichen planus (auto immune skin nodules), and mycosis fungoides (T-cell skin lymphoma).