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In the derivation of Washburn's equation, the inertia of the liquid is ignored as negligible. This is apparent in the dependence of length to the square root of time, , which gives an arbitrarily large velocity dL/dt for small values of t.
In the liver, bilirubin is conjugated with glucuronic acid by the enzyme glucuronyltransferase, first to bilirubin glucuronide and then to bilirubin diglucuronide, making it soluble in water: the conjugated version is the main form of bilirubin present in the "direct" bilirubin fraction. Much of it goes into the bile and thus out into the small ...
This is the numerator in the equation. The denominator is the total amount of sodium filtered by the kidneys. This is calculated by multiplying the plasma sodium concentration by the glomerular filtration rate (GFR) calculated using creatinine filtration. The flow rates then cancel out, simplifying to the standard equation: [1]
Unconjugated bilirubin is a breakdown product of heme (a part of hemoglobin in red blood cells). The liver is responsible for clearing the blood of unconjugated bilirubin, by 'conjugating' it (modified to make it water-soluble) through an enzyme named UDP-glucuronyl-transferase. When the total bilirubin level exceeds 17 μmol/L, it indicates ...
The rate therefore measured is the quantity of the substance in the urine that originated from a calculable volume of blood. Relating this principle to the below equation – for the substance used, the product of urine concentration and urine flow equals the mass of substance excreted during the time that urine has been collected.
This can be used to calculate mean values (expectations) of the flow rates, head losses or any other variables of interest in the pipe network. This analysis has been extended using a reduced-parameter entropic formulation, which ensures consistency of the analysis regardless of the graphical representation of the network. [3]
In most contexts a mention of rate of fluid flow is likely to refer to the volumetric rate. In hydrometry, the volumetric flow rate is known as discharge. Volumetric flow rate should not be confused with volumetric flux, as defined by Darcy's law and represented by the symbol q, with units of m 3 /(m 2 ·s), that is, m·s −1. The integration ...
Bilirubin di-glucuronide is a conjugated form of bilirubin formed in bilirubin metabolism. [1] The hydrophilic character of bilirubin diglucuronide enables it to be water-soluble. It is pumped across the hepatic canalicular membrane into the bile by the transporter MRP2 .