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Bromhexine is intended to support the body's mechanisms for clearing mucus from the respiratory tract.It is secretolytic, increasing the production of serous mucus in the respiratory tract, which makes the phlegm thinner and less viscous.
This mechanism is most likely responsible for the mucolytic effects of the drug, but may also explain the reported activity in Gaucher and Parkinson's disease. Both ambroxol and its parent drug bromhexine have been shown to induce autophagy in several cell types, and ambroxol was shown to potentiate rifampicin therapy in a model of tuberculosis ...
It is sold over the counter in France, Morocco, Egypt, Algeria, South Korea and the UAE [citation needed]. The oxomemazine ingredient (antihistamine) is not approved by the U.S. Food and Drug Administration (FDA), either for over the counter or prescription use. It is sold in France as cough syrup.
Guaifenesin might act as an expectorant by increasing the volume and reducing the viscosity of secretions in the trachea and bronchi via stimulation of the gastric mucosa. . This stimulation leads to an increased parasympathetic activity in the respiratory tract via the so-called gastro-pulmonary reflex, although some in vitro studies suggested that it might also act directly on the ...
Carbocisteine, also called carbocysteine, is a mucolytic that reduces the viscosity of sputum and so can be used to help relieve the symptoms of chronic obstructive pulmonary disorder (COPD) and bronchiectasis by allowing the sufferer to bring up sputum more easily.
In 1952, Vicks began selling cough syrup, and in 1959 they introduced Sinex Nasal Spray. [8] The company began selling NyQuil in 1966. [ 8 ] The parent company became Richardson-Merrell and then in 1982 divided into prescription drug company Merrell Dow (sold to Dow Chemical Company ) and over-the-counter drug company Richardson-Vicks which ...