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Peripheral blood smear in patient with thrombotic thrombocytopenic purpura. Typical schistocytes are annotated. A schistocyte (from Greek schistos for "divided" and kytos for "hollow" or "cell") is a fragmented part of a red blood cell. Schistocytes are sometimes referred to as helmet cells because of their irregular shape from mechanical force ...
The presence of three conditions: rheumatoid arthritis, an enlarged spleen (splenomegaly), and an abnormally low white blood cell count are indications that Felty's syndrome is possibly occurring. This condition as a whole is difficult to diagnose due to its complexity given a combination of disorders.
Primary polycythemias are myeloproliferative diseases affecting red blood cell precursors in the bone marrow. Polycythemia vera (PCV) (a.k.a. polycythemia rubra vera (PRV)) occurs when excess red blood cells are produced as a result of an abnormality of the bone marrow. [3] Often, excess white blood cells and platelets are also produced
The red cells are of normal size and color (normocytic and Normochromic). [32] A low white blood cell count usually only occurs in people with Felty's syndrome with an enlarged liver and spleen. The mechanism of neutropenia is complex. An increased platelet count occurs when inflammation is uncontrolled. [33]
Hemoglobin is a protein containing iron that facilitates the transportation of oxygen in red blood cells. [15] Hemoglobin in the blood carries oxygen from the lungs to the other tissues of the body, where it releases the oxygen to enable metabolism. A healthy level of hemoglobin for men is between 13.2 and 16.6 grams per deciliter, and in women ...
Typically, the cells of female humans contain two X chromosomes, while the cells of male humans have an X and a Y chromosome. [22] During early fetal development , all embryos have phenotypically female genitalia up until week 6 or 7, when a male embryo's gonads differentiate into testes due to the action of the SRY gene on the Y chromosome. [ 23 ]
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