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Fatigue in a medical context is used to cover experiences of low energy that are not caused by normal life. [2] [3]A 2021 review proposed a definition for fatigue as a starting point for discussion: "A multi-dimensional phenomenon in which the biophysiological, cognitive, motivational and emotional state of the body is affected resulting in significant impairment of the individual's ability to ...
Frail elderly patients (score of 4 or 5) have even worse outcomes, with the risk of being discharged to a nursing home rising to twenty times the rate for non-frail elderly people. Another tool that has been used to predict frailty outcome post-surgery is the Modifies Frailty Index, or mFI-5. This scale consists of 5 key co-morbidities: [62]
For the knee extensors, old adults produce less torque during dynamic or isometric maximal voluntary contractions than young adults. The mechanisms controlling fatigue in the elderly during isometric contractions are not the same as those that influence fatigue during dynamic contractions, while young adults keep the same strategy.
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That fatigue and related symptoms can be confused with symptoms of depression and dementia, he says. People with vitamin B12 deficiency may act forgetful and confused, and struggle with ...
Stress, hypometabolism, and oxidative damage may decrease physiologic reserve in the elderly and can lead to a decrease in neuron energy production and an increase in neuron damage. [12] Thioredoxin reductase is an antioxidant that neutralizes oxidative free radicals that can cause cell death. The brain is vulnerable to oxidative free radicals ...