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Triamcinolone acetonide, sold under the brand name Kenalog among others, is a synthetic corticosteroid medication used topically to treat various skin conditions, [13] to relieve the discomfort of mouth sores, and by injection into joints to treat various joint conditions.
Intralesional corticosteroid injections were introduced as a treatment in the mid-1960s as a method to attenuate scarring. [25] Pressure therapy has been used for prophylaxis and treatment of keloids since the 1970s. [25] Topical silicone gel sheeting was introduced as a treatment in the early 1980s. [25]
A hypertrophic scar is a cutaneous condition characterized by deposits of excessive amounts of collagen which gives rise to a raised scar, but not to the degree observed with keloids. [1] Like keloids, they form most often at the sites of pimples, body piercings , cuts and burns.
Hypertrophic scar. Silicone gel sheeting is the gold-standard and non-invasive treatment for hypertrophic and keloid scars. During skin injury repair, dermal cells proliferate and migrate from the skin tissue to the wound, producing collagen and causing contraction of the placement dermis. [5]
A long-term course of corticosteroid injections into the scar may help flatten and soften the appearance of keloid or hypertrophic scars. [54] Topical steroids are ineffective. [55] However, clobetasol propionate can be used as an alternative treatment for keloid scars. [56]
Hypertrophic scarring is a common development in wounds that take longer than two or three weeks to heal. This frequently happens weeks after the wound was closed. If compression is applied as soon as the wound heals and is kept at a pressure of about 24 mm Hg, raised scarring can be avoided.