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The focus of this article is a comprehensive view of modeling a neural network (technically neuronal network based on neuron model). Once an approach based on the perspective and connectivity is chosen, the models are developed at microscopic (ion and neuron), mesoscopic (functional or population), or macroscopic (system) levels.
A motor neuron (or motoneuron or efferent neuron [1]) is a neuron whose cell body is located in the motor cortex, brainstem or the spinal cord, and whose axon (fiber) projects to the spinal cord or outside of the spinal cord to directly or indirectly control effector organs, mainly muscles and glands. [2]
At the time of Henneman’s initial study of motor neuron recruitment, [1] it was known that neurons varied greatly in size, that is in the diameter and extent of the dendritic arbor, size of the soma, and diameter of axon. However, the functional significance of neuron size was not yet known.
One of the earliest models of the neuron was based on mathematical and physical modelling: the integrate-and-fire model, which was developed in 1907. Decades later, the discovery of the squid giant axon led Alan Hodgkin and Andrew Huxley (half-brother to Aldous Huxley) to develop the Hodgkin–Huxley model of the neuron in 1952. [8]
A motor pool consists of all individual motor neurons that innervate a single muscle. Each individual muscle fiber is innervated by only one motor neuron, but one motor neuron may innervate several muscle fibers. This distinction is physiologically significant because the size of a given motor pool determines the activity of the muscle it ...
A motor nerve, or efferent nerve, is a nerve that contains exclusively efferent nerve fibers and transmits motor signals from the central nervous system (CNS) to the muscles of the body. This is different from the motor neuron , which includes a cell body and branching of dendrites, while the nerve is made up of a bundle of axons.
In biology, a motor unit is made up of a motor neuron and all of the skeletal muscle fibers innervated by the neuron's axon terminals, including the neuromuscular junctions between the neuron and the fibres. [1] Groups of motor units often work together as a motor pool to coordinate the contractions of a single muscle. The concept was proposed ...
The spiking neuron model by Nossenson & Messer [72] [73] [74] produces the probability of the neuron firing a spike as a function of either an external or pharmacological stimulus. [72] [73] [74] The model consists of a cascade of a receptor layer model and a spiking neuron model, as shown in Fig 4. The connection between the external stimulus ...