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Hepatitis E. Hepatitis E is inflammation of the liver caused by infection with the hepatitis E virus (HEV); [4][5] it is a type of viral hepatitis. [6] Hepatitis E has mainly a fecal-oral transmission route that is similar to hepatitis A, although the viruses are unrelated. [7][8][9] HEV is a positive-sense, single-stranded, nonenveloped, RNA ...
Orthohepevirus A. The hepatitis E virus (HEV) is the causative agent of hepatitis E. It is of the species Orthohepevirus A.[a][2][1] Globally, approximately 939 million corresponding to 1 in 8 individuals have ever experienced HEV infection. About 15–110 million individuals have recent or ongoing HEV infection. [3]
Hepatitis. Alcoholic hepatitis as seen with a microscope, showing fatty changes (white circles), remnants of dead liver cells, and Mallory bodies (twisted-rope shaped inclusions within some liver cells). (H&E stain) Specialty. Infectious disease, gastroenterology, hepatology. Symptoms.
Koch's postulates. Robert Hermann Koch (11 December 1843 – 27 May 1910) was a German physician who developed Koch's postulates. [1] Koch's postulates (/ kɒx / KOKH) [2] are four criteria designed to establish a causal relationship between a microbe and a disease. The postulates were formulated by Robert Koch and Friedrich Loeffler in 1884 ...
Scientific career. Fields. Virology. Harvey James Alter (born September 12, 1935) is an American medical researcher, virologist, physician and Nobel Prize laureate, who is best known for his work that led to the discovery of the hepatitis C virus. [1] Alter is the former chief of the infectious disease section and the associate director for ...
Infectious diseases, gastroenterology. Viral hepatitis is liver inflammation due to a viral infection. [1][2] It may present in acute form as a recent infection with relatively rapid onset, or in chronic form, typically progressing from a long-lasting asymptomatic condition up to a decompensated hepatic disease and hepatocellular carcinoma (HCC).
A viral disease (or viral infection) occurs when an organism's body is invaded by pathogenic viruses, and infectious virus particles (virions) attach to and enter susceptible cells. [1] Examples are the common cold, gastroenteritis and pneumonia. [2]
Sir Michael Houghton (born 1949) is a British scientist and Nobel Prize laureate. Along with Qui-Lim Choo, George Kuo and Daniel W. Bradley, he co-discovered Hepatitis C in 1989. [2] He also co-discovered the Hepatitis D genome in 1986. [3] The discovery of the Hepatitis C virus (HCV) led to the rapid development of diagnostic reagents to ...