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Buspirone, sold under the brand name Buspar among others, is an anxiolytic, a medication primarily used to treat anxiety disorders, particularly generalized anxiety disorder (GAD). [ 10 ] [ 11 ] It is a serotonin 5-HT 1A receptor partial agonist , increasing action at serotonin receptors in the brain. [ 3 ]
Buspirone (Buspar): Grapefruit juice increased peak and AUC plasma concentrations of buspirone 4.3- and 9.2-fold, respectively, in a randomized, 2-phase, ten-subject crossover study. [ 68 ] Codeine is a prodrug that produces its analgesic properties following metabolism to morphine entirely by CYP2D6.
Cerebrovascular accident (stroke); Myocardial infarction (heart attack); Cardiomyopathy; Congestive heart failure; Bradycardia; Dysphoria; Hallucinations; Feelings of ...
Other medications, like buspirone. ... While effective, they’re more likely to cause side effects and drug interactions than newer antidepressants used to treat anxiety.
Organ-transplant rejection drugs, including Sandimmune and Neoral (cyclosporine) Some anti-anxiety medications, such as BuSpar (buspirone) Drugs to treat heart rhythm issues, like Cordarone and ...
Buspirone is sometimes used off-label to reduce sexual dysfunction associated with the use of SSRIs. [55] [56] [57] A number of non-SSRI drugs are not associated with sexual side effects (such as bupropion, mirtazapine, tianeptine, agomelatine, tranylcypromine, and moclobemide [58] [59] [60]).
The researchers found that both SGLT2 inhibitors and GLP-1 agonists were associated with a lower risk of major cardiovascular events, but the drug effects varied with the patients’ age.
The most significant risk associated with the use of MAOIs is the potential for drug interactions with over-the-counter, prescription, or illegally obtained medications, and some dietary supplements (e.g., St. John's wort or tryptophan). It is vital that a doctor supervise such combinations to avoid adverse reactions.