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This is a list of investigational autism and pervasive developmental disorder drugs, or drugs that are currently under development for clinical use in the treatment of autistic spectrum disorders and/or other pervasive developmental disorders but are not yet approved.
Use of anticonvulsant medications should be carefully monitored during use in pregnancy. [94] For example, since the first trimester is the most susceptible period for fetal development, planning a routine antiepileptic drug dose that is safer for the first trimester could be beneficial to prevent pregnancy complications. [95]
Keppra (levetiracetam) – an anticonvulsant drug which is sometimes used as a mood stabilizer and has potential benefits for other psychiatric and neurologic conditions such as Tourette syndrome, anxiety disorder, and Alzheimer's disease; Klonopin – anti-anxiety and anti-epileptic medication of the benzodiazepine class
Convulsant drugs (the functional opposites of anticonvulsants) will always induce seizures at sufficient doses. Examples of such agents — some of which are used or have been used clinically and others of which are naturally occurring toxins — include strychnine , bemegride , flumazenil , cyclothiazide , flurothyl , pentylenetetrazol ...
An off-label prescription drug has been shown to help children with autism gain the ability to speak. Leucovorin is used for cancer patients, but doctors are pushing for its approval for autism.
Levetiracetam, sold under the brand name Keppra among others, is a novel antiepileptic drug [7] used to treat epilepsy. [8] It is used for partial-onset, myoclonic, or tonic–clonic seizures, [7] and is taken either by mouth as an immediate or extended release formulation or by injection into a vein.
Aribit (Aripiprazole) tablets. Aripiprazole, sold under the brand name Abilify, among others, is an atypical antipsychotic [14] primarily used in the treatment of schizophrenia, bipolar disorder, and irritability associated with autism spectrum disorder; [14] other uses include as an add-on treatment for major depressive disorder and tic disorders. [14]
Anticonvulsants. The mainstay treatment of epilepsy is anticonvulsant medications, possibly for the person's entire life. [26] The choice of anticonvulsant is based on seizure type, epilepsy syndrome, other medications used, other health problems, and the person's age and lifestyle. [147]