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Medicinal fungi are fungi that contain metabolites or can be induced to produce metabolites through biotechnology to develop prescription drugs. Compounds successfully developed into drugs or under research include those treating infection with amoeba , bacteria , fungus , virus , inhibitors of cholesterol and ergosterol synthesis, and ...
Before oral antifungal therapies are used to treat nail disease, a confirmation of the fungal infection should be made. [36] Approximately half of suspected cases of fungal infection in nails have a non-fungal cause. [36] The side effects of oral treatment are significant and people without an infection should not take these drugs. [36]
Fungi cause the majority of plant diseases, which in turn cause serious economic losses. Sometimes, as in the Great Irish Famine of 1845–1849, fungal diseases of plants, in this case potato blight caused by Phytophthora, result in large-scale human suffering. Fungi are similarly the main cause of economic losses of timber in buildings.
Amphotericin B is an antifungal medication used for serious fungal infections and leishmaniasis. [3] The fungal infections it is used to treat include mucormycosis, aspergillosis, blastomycosis, candidiasis, coccidioidomycosis, and cryptococcosis. [4] For certain infections it is given with flucytosine. [5] It is typically given intravenously. [4]
Miconazole is a widely used topical antifungal medication for the treatment of many fungal infections, namely skin infections, nail infections and vaginal candidiasis. The drug is usually formulated in creams, powders and sprays. However, it is suggested that patients developing acute porphyrias should avoid using this drug.
Ketoconazole, sold under the brand name Nizoral, among others, is an antiandrogen, antifungal, and antiglucocorticoid medication used to treat a number of fungal infections. [11] Applied to the skin it is used for fungal skin infections such as tinea, cutaneous candidiasis, pityriasis versicolor, dandruff, and seborrheic dermatitis. [12]