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Mechanism of uniport transport across cell membrane. Uniporters work to transport molecules or ions by passive transport across a cell membrane down its concentration gradient. Upon binding and recognition of a specific substrate molecule on one side of the uniporter membrane, a conformational change is triggered in the transporter protein. [27]
The mechanism of antiporter transport involves several key steps and a series of conformational changes that are dictated by the structural element described above: [7] The substrate binds to its specific binding site on the extracellular side of the plasma membrane, forming a temporary substrate-bound open form of the antiporter.
In terms of membrane transport the gradient is of interest as it contributes to decreased system entropy in the co-transport of substances against their gradient. One of the most important pumps in animal cells is the sodium potassium pump, that operates through the following mechanism: [9]
Intracellular transport is the movement of vesicles and substances within a cell. Intracellular transport is required for maintaining homeostasis within the cell by responding to physiological signals. [1] Proteins synthesized in the cytosol are distributed to their respective organelles, according to their specific amino acid’s sorting ...
The sodium–potassium pump (a type of P-type ATPase) is found in many cell (plasma) membranes and is an example of primary active transport.Powered by ATP, the pump moves sodium and potassium ions in opposite directions, each against its concentration gradient.
Solute pumping is a form of active transport of a solute through a cell membrane.Solute pumping allows a molecule that cannot regularly cross the lipid bilayer (because of concentration gradient, polarity, or other reasons) to enter the cell by way of a protein channel.
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