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Most head and neck cancers caused by HPV are in the throat, in the base of the tongue and the tonsils. Most people who have high-risk HPV won’t get cancer. However, some people aren’t able to get rid of their HPV infection. When this happens, the virus can cause damage that makes a tumor grow.
In more recent decades, HPV has been shown as a risk factor for developing head and neck cancer. Head and neck cancer covers everything from throat, tongue, and tonsil cancer to laryngeal,...
Some people with HPV-related head and neck cancer have a higher risk of recurrence. David Routman, M.D. , a Mayo Clinic radiation oncologist, is leading a study investigating the use of an HPV vaccine with or without immunotherapy before surgery to prevent recurrence of throat cancer.
Johns Hopkins Medicine's head and neck cancer experts highlight the available resources from their multidisciplinary program to treat HPV-related head and neck cancers, including advanced imaging, dentistry, speech pathology, immunotherapy, surgery, robotic surgery and open clinical trials.
Frequently Asked Questions about HPV Head and Neck Cancers. Johns Hopkins head and neck surgeon Carole Fakhry answers questions about oral HPV, the HPV vaccine and recommendations for the vaccine’s use.
The majority of HPV-associated head and neck cancers (HPV + HNC) are caused by HPV16; additionally, co-factors such as smoking and immunosuppression contribute to the progression of HPV + HNC by interfering with tumor suppressor miRNA and impairing mediators of the immune system.
Head and neck cancers include cancers that start in the mouth, throat, sinuses and salivary glands. In general, head and neck cancer starts when a cell in the head and neck area develops changes in its DNA.
Head and neck cancers not related to HPV infection are especially likely to recur after treatment. Depending on the type of cancer, medical check-ups could include exams of the stoma, if one has been created, and of the mouth, neck, and throat.
Head and neck cancer diagnosis often begins with an exam of the head and neck area. Other tests might include imaging tests and a procedure to remove some cells for testing. The tests used for diagnosis may depend on the cancer's location.
Head and neck cancer includes several types of cancers that affect your mouth, throat or other parts of your head and neck. The most common symptom is a persistent sore throat. You can reduce your risk by avoiding tobacco, limiting alcohol and getting the HPV vaccine.