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Association mapping has been most widely applied to the study of human disease, specifically in the form of a genome-wide association study (GWAS). A genome-wide association study is performed by scanning an entire genome for SNPs associated with a particular trait of interest, or in the case of human disease, with a particular disease of interest.
QTL location is indicated only by looking at which markers give the greatest differences between genotype group averages, and the apparent QTL effect at a marker will be smaller than the true QTL effect as a result of recombination between the marker and the QTL. Second, we must discard individuals whose genotypes are missing at the marker.
Relationship between the minor allele frequency and the effect size of genome wide significant variants in a GWAS of height. Attempts have been made at creating comprehensive catalogues of SNPs that have been identified from GWA studies. [33] As of 2009, SNPs associated with diseases are numbered in the thousands. [34]
Atlanta Gas Light, is the largest natural gas distributor in the Southeast and is headquartered in Atlanta. It was founded in 1856 to install gas streetlights in Atlanta. The company now distributes natural gas to more than 1.6 million residential, commercial, and industrial customers in 200 communities throughout the state of Georgia ...
The wholesale division was known as Atlanta Gas Light Services (AGLS) for some time. In late September 2007, the Georgia Public Service Commission voted to allow AGL to construct a pipeline from the shipping terminal at Elba Island to connect with other pipelines across the state, via a pipeline that already runs across the mid-state.
The only considerable difference is that eQTL studies can involve a million or more expression microtraits. Standard gene mapping software packages can be used, although it is often faster to use custom code such as QTL Reaper or the web-based eQTL mapping system GeneNetwork.
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